College of Medicine, Florida State University, Tallahassee, FL, 32304, USA. Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd., Orlando, FL, 32827, USA. Faculdade de Nutrição, Universidade Federal de Pelotas, Pelotas, RS, Brazil. Faculdade de Medicina, Universidade de Fortaleza, Fortaleza, CE, Brazil. Departments of Molecular Pharmacology, Medicine, and the Institute for Aging Research, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. Edison Biotechnology Institute, Ohio University, Athens, OH, 45701, USA. Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, 45701, USA. Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA. Geriatric Research Education and Clinical Center (GRECC), Audie L. Murphy VA Hospital, South Texas Veterans Health Care System, San Antonio, TX, 78229, USA. Barshop Institute for Longevity and Aging Studies, San Antonio Geriatric, Research, Education and Clinical Center, San Antonio, TX, 78229, USA. Departments of Internal Medicine and Physiology, Southern Illinois University School of Medicine, Springfield, IL, USA. Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, 55905, USA. Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd., Orlando, FL, 32827, USA. michal.masternak@ucf.edu.